Simplify IGF2BP1 staining with this comprehensive IHC kit, featuring pre-optimized reagents for a straightforward antigen retrieval to mounting procedure.
Description
IGF2BP1 (CRDBP, VICKZ1, ZBP1) is a 577 amino acid protein in the RRM IMP/VICKZ family. It forms homodimers and heterodimers with IGF2BP1 and IGF2BP3. IGF2BP1 is mainly expressed in the embryo (fetal liver, lung, kidney, thymus) and in gonocytes, testis, spermatogonia, semen, oocytes, and placenta. It is expressed in cancers, including testis, lung, kidney, prostate, and trachea. IGF2BP1 is an RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes, shielding them from degradation.
Features
Ready to use High Sensitivity Streptavidin (HSS) increases detection sensitivity Suitable for tissue sections & cytospin preparations Pre-diluted reagents minimize hands-on time Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
IGF2BP1
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody Secondary Antibody Antigen Unmasking Buffer Washing Buffer Blocking Buffer Color Development Reagent 1 Color Development Reagent 323 Signal Amplification Reagent Contrast Staining Agent Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
CRDBP; IGF II mRNA binding protein 1; IGF2 mRNA binding protein 1; IGF2BP1; IMP1; VICKZ family member 1; VICKZ1; ZBP1; Zip code binding protein 1; Zipcode binding protein 1
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls: - Positive control: a section from a tissue known to express the protein of interest. - Negative control: a section from a tissue known not to express the target antigen. - Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source) Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation) Tissue Embedding Media Tissue Staining Kit (Optional)