OncoIHC™ YTHDC1 Ready-To-Use IHC Kit (CAT#: ITS-1122-ZP5297)

Ensure consistent YTHDC1 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.

YTHDC1, containing 1 YTH domain, is an m6A-binding protein that recognizes and binds to m6A methylation sites, playing a specific role in gene expression. It is constitutively enriched in the nucleus and regulates mRNA splicing by bridging interactions between trans- and cis-regulatory elements. YTHDC1 mediates the export of m6A-modified mRNA from the nucleus to the cytoplasm by interacting with SRSF3, which is involved in tumorigenic processes in breast cancer, colon cancer, ovarian cancer, osteosarcoma, and glioblastoma.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

YTHDC1

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue