OncoIHC™ YTHDC1 Ready-To-Use IHC Kit

Ensure consistent YTHDC1 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.

YTHDC1, containing 1 YTH domain, is an m6A-binding protein that recognizes and binds to m6A methylation sites, playing a specific role in gene expression. It is constitutively enriched in the nucleus and regulates mRNA splicing by bridging interactions between trans- and cis-regulatory elements. YTHDC1 mediates the export of m6A-modified mRNA from the nucleus to the cytoplasm by interacting with SRSF3, which is involved in tumorigenic processes in breast cancer, colon cancer, ovarian cancer, osteosarcoma, and glioblastoma.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

YTHDC1

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 608
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

KIAA1966; Putative splicing factor YT521; YT521; YT521B; YTH domain containing 1; YTHDC1

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)