OXPHOSight™ Creatine Kinase Assay Kit

CAT#: ITS-1125-HM17
Product Type: Assay Kit
Species: All Species
Brand: OXPHOSight
Development Stage: Research-Grade Metabolic Assay Development
Short Description
Quantifies CK enzyme activity.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Creatine Kinase Assay Kit quantifies cardiac and skeletal muscle injury markers, which is critical for the safety profiling of statins and other potentially myotoxic pharmaceutical agents. This sensitive kinetic assay enables the early detection of off-target muscle toxicity during drug development. It provides essential data for risk assessment, ensuring that new therapies do not compromise muscle integrity.
Features
Sensitive kinetic assay for quantifying muscle injury biomarkers; Essential for monitoring off-target myotoxicity in statin and kinase inhibitor development.
Process Relevance
Myotoxicity Screening
Application Stage
Pre-clinical Safety
Applications
Marker for muscle damage (rhabdomyolysis) and myocardial infarction.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 340 nm
Sample Type
Serum, plasma samples
Research Areas
Cardiology; Muscle Physiology
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 40 min
LOD
5 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Creatine Kinase (CK) catalyzes the reversible phosphorylation of creatine to phosphocreatine. Clinically specific CK isoenzymes are used as biomarkers for myocardial infarction and skeletal muscle damage.
For Research Use Only | Not For Clinical Use
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