Short Description
Measures hexokinase activity.
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Hexokinase Assay Kit evaluates the rate-limiting first step of glucose metabolism, supporting the discovery of metabolic modulators for diabetes and cancer treatment. By measuring glucose phosphorylation rates, researchers can validate the efficacy of compounds that alter glycolytic flux. This assay is crucial for metabolic reprogramming studies, helping to identify novel therapeutic targets in diseases characterized by altered glucose uptake.
Features
Measures rate-limiting glycolytic activity; Validates metabolic reprogramming agents in oncology and diabetes drug discovery.
Process Relevance
Cancer Metabolism Targeting
Application Stage
Target Validation
Applications
Glycolysis regulation studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Oncology; Diabetes & Obesity
Datasheet