Development Stage: Research-Grade Metabolic Assay Development
Short Description
Specific measurement of L-lactate isomer.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ L-Lactate Assay Kit provides specific measurement of the L-isomer, critical for monitoring the Warburg effect and lactate shuttle in tumors. This assay validates glycolytic inhibitors and drugs that target lactate transport (MCTs). It supports the evaluation of metabolic reprogramming in cancer and the assessment of lactate clearance in toxicology models.
Features
Specific for L-isomer; Critical for monitoring the Warburg effect and lactate shuttle in tumors.
Process Relevance
Warburg Effect Characterization
Application Stage
Pre-clinical Efficacy
Applications
Monitoring aerobic glycolysis (Warburg effect).
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, plasma, cell culture media, samples
Research Areas
Oncology; Critical Care Medicine
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 20 min
LOD
0.05 mM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
L-Lactate is the physiological isomer of lactate produced by anaerobic glycolysis. Its accumulation (lactic acidosis) indicates tissue hypoxia or mitochondrial dysfunction.