OXPHOSight™ NADP+/NADPH Assay Kit

CAT#: ITS-1125-HM39
Product Type: Assay Kit
Species: All Species
Brand: OXPHOSight
Development Stage: Research-Grade Metabolic Assay Development
Short Description
Quantifies the coenzymes NADP and NADPH.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ NADP+/NADPH Assay Kit analyzes the cellular reducing power required for biosynthesis and detoxification, key for understanding drug mechanisms involving oxidative stress. Ultrasensitive detection of cofactor ratios validates biosynthetic capacity and redox status in mechanism-of-action (MoA) studies. This assay provides critical insights into how drugs affect cellular resilience and anabolic pathways in cancer and toxicology research.
Features
Ultrasensitive detection of cofactor ratios; Validates biosynthetic capacity and redox status in mechanism-of-action (MoA) studies.
Process Relevance
Cellular Redox Status
Application Stage
Discovery / Mechanistic Tox
Applications
Investigates redox states and lipid synthesis pathways.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Colorimetric Determination at 565 nm
Sample Type
Cells, Tissue
Research Areas
Metabolic Disease; Oxidative Stress
Size
100 tests
Data Output Type
Quantitative (Ratio / Concentration)
Assay Time
Results in 30 min
LOD
0.1 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
NADP+ and its reduced form NADPH are cofactors essential for anabolic reactions like lipid synthesis. NADPH also provides the reducing equivalents for maintaining the glutathione antioxidant system.
For Research Use Only | Not For Clinical Use
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