Short Description
Quantifies the coenzymes NADP and NADPH.
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ NADP+/NADPH Assay Kit analyzes the cellular reducing power required for biosynthesis and detoxification, key for understanding drug mechanisms involving oxidative stress. Ultrasensitive detection of cofactor ratios validates biosynthetic capacity and redox status in mechanism-of-action (MoA) studies. This assay provides critical insights into how drugs affect cellular resilience and anabolic pathways in cancer and toxicology research.
Features
Ultrasensitive detection of cofactor ratios; Validates biosynthetic capacity and redox status in mechanism-of-action (MoA) studies.
Process Relevance
Cellular Redox Status
Application Stage
Discovery / Mechanistic Tox
Applications
Investigates redox states and lipid synthesis pathways.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Colorimetric Determination at 565 nm
Research Areas
Metabolic Disease; Oxidative Stress
Datasheet