PC3 In Vitro RNA Expression Analysis Assay (DNA Microarray)
CAT#: ITS-1022-YF1872
Target Cell Organism: Human
Target Cell Alternative Name: PC-3
Target Cell Name: PC3
Assay Type: Gene and Protein Expression Assays
Assay Overview
This assay is to provide PC3-based In Vitro RNA Expression Analysis Assay (DNA Microarray) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
PC3
Target Cell Organism
Human
Target Cell Background
PC3 (PC-3) is a human prostate cancer cell line used in prostate cancer research and drug development. PC3 cells are useful in investigating biochemical changes in advanced prostate cancer cells and in assessing their response to chemotherapeutic agents. PC3 cells are also used to study viral infection in mammalian cells that exhibit an immune response.
Target Cell Alternative Name
PC-3
Related Diseases
Prostate Cancer
Research Area
Oncology
Assay Name
In Vitro RNA Expression Analysis Assay (DNA Microarray)
Short Description
PC3-cell based In Vitro RNA Expression Analysis Assay (DNA Microarray)
Assay Description
DNA microarray is another technique that enables the analysis of gene expression. Fluorescent labeled cDNA (with cyanines) synthesized from a test sample is hybridized to target probes with complementary sequences attached on microarray chips and strongly bound complexes are screened after scanning optically.
Assay Type
Gene and Protein Expression Assays
Assay Type Details
Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.