Reh In Vitro Mitotic Index Assay (Cell Proliferation)
CAT#: ITS-1122-YF4843
Target Cell Organism: Human
Target Cell Name: Reh
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide Reh-based In Vitro Mitotic Index Assay (Cell Proliferation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Reh
Target Cell Organism
Human
Target Cell Background
Reh is a human cell line exhibiting lymphoblastic morphology that was isolated from tissue from an acute lymphocytic leukemia (ALL) patient. Use these cells in your immune system disorder and cancer research.
Related Diseases
Acute Lymphocytic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro Mitotic Index Assay (Cell Proliferation)
Short Description
Reh-cell based In Vitro Mitotic Index Assay (Cell Proliferation)
Assay Description
Mitotic index assay is one of the old assays used to determine the number of cells that are undergoing mitosis in a specified cell population using monoclonal antibodies specific for phosphorylated histone H3 (ser28). Phosphorylated histone H3 (ser28) is considered as a main marker for mitosis and this specific phosphorylation can be utilized to calculate the mitotic index in a specified cell population.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.