Sedoheptulose 7-Phosphate-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR121
Cell Type: M1 macrophages
RNA writers: PCIF1
RNA readers: /
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: m1A
RNA editing: A to I
Short Description
This product is a Sedoheptulose 7-phosphate-targeted RNA modification and metabolomics analysis tool based on the m1A (PCIF1-FTO-HDACs-spacer C9) modification and Mevalonate pathway-mediated (CPEB4-Acetyl-CoA-ADP) metabolic analysis system.
RNA writers
PCIF1
RNA readers
/
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
m1A
Label
spacer C9
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m1A-PCIF1-FTO-HDACs-spacer C9
Substrates
Acetyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
TET3 overexpression
Metabolic alteration
Upregulating glucose metabolism
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
CPEB4
Metabolic Reprogramming
Mevalonate pathway-CPEB4-Acetyl-CoA-ADP
Target
Sedoheptulose 7-phosphate
Alternative Names
Sedoheptulose 7-phosphate
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.