SHP-77 In Vitro Micro-carrier Beads Assay (Angiogenesis)
CAT#: ITS-0123-YF2470
Target Cell Organism: Human
Target Cell Name: SHP-77
Assay Type: Angiogenesis Monitoring Assays
Assay Overview
This assay is to provide SHP-77-based In Vitro Micro-carrier Beads Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
SHP-77
Target Cell Organism
Human
Target Cell Background
SHP-77 epithelial cells are derived from a non-encapsulated primary lung tumor from the apical portion of the upper lobe of the left lung of a 54-year-old, White male in 1977. SHP-77 cells can serve as an in vitro target in 51Cr and 111 in release cytotoxicity assays as well as in vivo nude mice assays for evaluating immune reactivity of cells and serum from lung cancer patients. The cells can be used to evaluate the immune status of patients with SCLC who are treated with radiation or chemotherapy.
Related Diseases
Lung Cancer
Research Area
Oncology
Assay Name
In Vitro Micro-carrier Beads Assay (Angiogenesis)
Assay Description
Migration of cells from cell-coated micro-carrier beads to the surface of cell culture wells or dishes is measured in this assay. Cells are grown on the surface of carrieer beads and beads are then placed in a plate well or dish over particular incubation periods.
Assay Type
Angiogenesis Monitoring Assays
Assay Type Details
Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).