SK-ES-1 In Vitro Post-translational Modifications Assay
CAT#: ITS-1122-YF2299
Target Cell Organism: Human
Target Cell Name: SK-ES-1
Assay Type: Gene and Protein Expression Assays
Assay Overview
This assay is to provide SK-ES-1-based In Vitro Post-translational Modifications Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
SK-ES-1
Target Cell Organism
Human
Target Cell Background
SK-ES-1 is a human Ewing sarcoma (anaplastic osteosarcoma) cell line that displays epithelial morphology and grows in adherent tissue culture.
Related Diseases
Ewing Sarcoma
Research Area
Oncology
Assay Name
In Vitro Post-translational Modifications Assay
Short Description
SK-ES-1-cell based In Vitro Post-translational Modifications Assay
Assay Description
Immunoassays and mass spectrometry techniques are considered ideal techniques for the detection of post-translational modification. Both the genetic and epigenetic modifications have contributed to the initiation and progression of cancer.
Assay Type
Gene and Protein Expression Assays
Assay Type Details
Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.