SW 780 In Vitro Post-translational Modifications Assay
CAT#: ITS-1022-YF3139
Target Cell Organism: Human
Target Cell Alternative Name: SW-780, SW780
Target Cell Name: SW 780
Assay Type: Gene and Protein Expression Assays
Assay Overview
This assay is to provide SW 780-based In Vitro Post-translational Modifications Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
SW 780
Target Cell Organism
Human
Target Cell Background
The SW 780 line was established in 1974 by A. Leibovitz from a grade I transitional cell carcinoma.
Target Cell Alternative Name
SW-780, SW780
Related Diseases
Bladder Cancer
Research Area
Oncology
Assay Name
In Vitro Post-translational Modifications Assay
Short Description
SW 780-cell based In Vitro Post-translational Modifications Assay
Assay Description
Immunoassays and mass spectrometry techniques are considered ideal techniques for the detection of post-translational modification. Both the genetic and epigenetic modifications have contributed to the initiation and progression of cancer.
Assay Type
Gene and Protein Expression Assays
Assay Type Details
Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.