T24 In Vitro Post-translational Modifications Assay

This assay is to provide T24-based In Vitro Post-translational Modifications Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

T24

Human

The T24 cell line was established from a transitional cell carcinoma of the bladder in a female patient in 1973. Reports in the literature indicated a wide range of tumorigenicity for T24 when injected subcutaneously in immunocompromised murine hosts.

Bladder Cancer

Oncology

In Vitro Post-translational Modifications Assay

T24-cell based In Vitro Post-translational Modifications Assay

Immunoassays and mass spectrometry techniques are considered ideal techniques for the detection of post-translational modification. Both the genetic and epigenetic modifications have contributed to the initiation and progression of cancer.

Gene and Protein Expression Assays

Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.