U87 MG In Vitro Mitotic Index Assay (Cell Proliferation)

CAT#: ITS-1022-YF328
Target Cell Organism: Human
Target Cell Alternative Name: U87MG; U-87 MG
Target Cell Name: U87 MG
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide U87 MG-based In Vitro Mitotic Index Assay (Cell Proliferation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
U87 MG
Target Cell Organism
Human
Target Cell Background
U-87 MG is a cell line with epithelial morphology that was isolated from malignant gliomas from a male patient, likely with Glioblastoma. Use these cells in your neuroscience and immuno-oncology research.
Target Cell Alternative Name
U87MG; U-87 MG
Related Diseases
Glioblastoma
Research Area
Oncology
Assay Name
In Vitro Mitotic Index Assay (Cell Proliferation)
Short Description
U87 MG-cell based In Vitro Mitotic Index Assay (Cell Proliferation)
Assay Description
Mitotic index assay is one of the old assays used to determine the number of cells that are undergoing mitosis in a specified cell population using monoclonal antibodies specific for phosphorylated histone H3 (ser28). Phosphorylated histone H3 (ser28) is considered as a main marker for mitosis and this specific phosphorylation can be utilized to calculate the mitotic index in a specified cell population.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Proliferation Assay
Assay MOA
Cell-based Assays Based on DNA Synthesis
For Research Use Only | Not For Clinical Use
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