U87 MG In Vitro S-nitrosylation Assay (Oxidative Stress)

This assay is to provide U87 MG-based In Vitro S-nitrosylation Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

U87 MG

Human

U-87 MG is a cell line with epithelial morphology that was isolated from malignant gliomas from a male patient, likely with Glioblastoma. Use these cells in your neuroscience and immuno-oncology research.

U87MG; U-87 MG

Glioblastoma

Oncology

In Vitro S-nitrosylation Assay (Oxidative Stress)

U87 MG-cell based In Vitro S-nitrosylation Assay (Oxidative Stress)

S-nitrosylation (attachment of NO to thiol side chains of the amino acid cysteine) and S-glutathionylation (attachment of GSH to thiol side chains of the amino acid cysteine) are two post-translational modification processes reported to increase with oxidative stress.

Oxidative Stress Assays

Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.

Markers Thiobarbituric Acid Reactive Substances