4T1 In Vitro Micro-carrier Beads Assay (Angiogenesis)

This assay is to provide 4T1-based In Vitro Micro-carrier Beads Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

4T1

Mouse

4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. 4T1 cells are epithelial and are resistant to 6-thioguanine. In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes, brain and bone.

Breast Cancer

Oncology

In Vitro Micro-carrier Beads Assay (Angiogenesis)

4T1-cell based In Vitro Micro-carrier Beads Assay (Angiogenesis)

Migration of cells from cell-coated micro-carrier beads to the surface of cell culture wells or dishes is measured in this assay. Cells are grown on the surface of carrieer beads and beads are then placed in a plate well or dish over particular incubation periods.

Angiogenesis Monitoring Assays

Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular
network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).