ABA3-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR231
Cell Type: DCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: LDH
RNA types: rRNA
Modification: m7G
RNA editing: C to U
Short Description
This product is a ABA3-targeted RNA modification and metabolomics analysis tool based on the m7G (METTL14-YTHDF2-ALKBH5-LDH-spacer C18) modification and Mevalonate pathway-mediated (FMRP-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
LDH
RNA types
rRNA
Modification
m7G
Label
spacer C18
RNA editing
C to U
Cell Type
DCs
Oligonucleotide
2'-MOE
RNA Construction
rRNA-m7G-METTL14-YTHDF2-ALKBH5-LDH-spacer C18
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
SETD2 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation andfatty acid synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
FMRP
Metabolic Reprogramming
Mevalonate pathway-FMRP-Succinyl-CoA-α-KG
Target
ABA3
Alternative Names
Molybdenum cofactor sulfurtransferase (ABA3; MoCo sulfurase; MoCo sulfurtransferase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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