AccuMetab™ Canine CYP2D15 Enzyme, Catalytically Active

CAT#: ITS-0426-YL37
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Canine CYP2D15 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
As the canine functional equivalent to human CYP2D6, CYP2D15 metabolizes various basic amines and cardiovascular agents. However, its distinct lack of human-like polymorphism makes it a vital comparative tool for establishing baseline non-polymorphic clearance in preclinical species selection.
Key Features
Canine equivalent to human CYP2D6; Non-polymorphic baseline for preclinical clearance; Essential for veterinary cardiovascular drug profiling; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Veterinary Pharmacology
Species
Beagle
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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