ConjuLink™ Human Blood-based SULT1A1 / Sulfotransferase 1A1 ELISA Kit

CAT#: ITS-0326-WB10
Product Type: ELISA Kit
Species: Human
Target: Human sulfotransferase 1A1 (SULT1A1)
Brand: ConjuLink™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies human SULT1A1 levels in blood samples using a sensitive sandwich ELISA format.
Brand
ConjuLink™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
ConjuLink™ Human Blood-based SULT1A1 / Sulfotransferase 1A1 ELISA Kit enables precise quantification of SULT1A1 protein in human blood-derived samples using a highly specific sandwich ELISA platform. The assay utilizes optimized antibody pairs for selective detection of sulfotransferase 1A1, supporting reliable measurement of enzyme expression in pharmacological, toxicological, and metabolic research studies.
Features
Highly specific antibody pairs ensure selective detection of human SULT1A1 protein, minimizing cross-reactivity with related sulfotransferase isoforms.
Sensitive sandwich ELISA design enables reliable quantification of low-abundance enzyme levels in human serum, plasma, or other blood-derived samples.
Standardized microplate workflow supports reproducible measurements and straightforward integration into routine laboratory and pharmacological research assays.
Pre-validated reagents and optimized buffers improve assay consistency and reduce variability across experimental runs.
Process Relevance
Measures circulating SULT1A1 levels to evaluate metabolic enzyme expression and xenobiotic detoxification capacity.
Application Stage
Biomarker research, pharmacogenomic studies, toxicology investigations, and drug metabolism analysis.
Applications
Quantitative measurement of SULT1A1 protein in human serum or plasma, metabolic enzyme profiling, biomarker research, pharmacological studies, ADME profiling studies, and investigations of xenobiotic detoxification pathways.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Human sulfotransferase 1A1 (SULT1A1)
Detection Method
Colorimetric - 450nm (TMB)
Sample Type
Plasma, serum
Assay Measures
Quantitative
Research Areas
Drug metabolism & pharmacokinetics (ADME), toxicology, pharmacology, enzymology, biomarker research, xenobiotic metabolism, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using colorimetric sandwich ELISA detection.
Assay Range
0.156 - 10 ng/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Sulfotransferase 1A1 (SULT1A1) is a major cytosolic Phase II metabolic enzyme responsible for transferring sulfate groups to phenolic compounds, hormones, and xenobiotics. This conjugation process enhances solubility and facilitates elimination. Variation in SULT1A1 expression can influence metabolic detoxification capacity and affect the pharmacokinetics of numerous therapeutic compounds.
Pathways
SULT1A1 participates in the Phase II sulfation pathway of xenobiotic metabolism, catalyzing sulfate conjugation using the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS). These reactions frequently follow Phase I oxidative metabolism mediated by cytochrome P450 enzymes. The coordinated action of these pathways regulates detoxification, hormone metabolism, and clearance of environmental chemicals.
For Research Use Only | Not For Clinical Use
Online Inquiry