Acetone-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR329
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: tRNA
Modification: m7G
RNA editing: A to I
Short Description
This product is a Acetone-targeted RNA modification and metabolomics analysis tool based on the m7G (METTL14-YTHDF2-ALKBH5-HDACs-spacer C18) modification and Fatty acid synthesis-mediated (TDP-43-SAM-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
tRNA
Modification
m7G
Label
spacer C18
RNA editing
A to I
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-m7G-METTL14-YTHDF2-ALKBH5-HDACs-spacer C18
Substrates
SAM
Cofactors
α-KG
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Fatty acid synthesis-TDP-43-SAM-α-KG
Target
Acetone
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.