ADP-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR88
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: ACOT12
RNA types: mRNAs
Modification: m6Am
RNA editing: T to C
Short Description
This product is a ADP-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-ACOT12-HEX) modification and PPP-mediated (hnRNPs-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
ACOT12
RNA types
mRNAs
Modification
m6Am
Label
HEX
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-ACOT12-HEX
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
PPP
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
PPP-hnRNPs-Lactyl-CoA-ADP
Target
ADP
Alternative Names
Adenosine diphosphate (ADP
Gene ID
142(Human);11545(Mouse)
UniProt ID
P09874(Human);P11103(Mouse)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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