OTC-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR216
Cell Type: MDSCs
RNA writers: DNMT2
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: KMTs
RNA types: rRNA
Modification: ψ
RNA editing: T to C
Short Description
This product is a OTC-targeted RNA modification and metabolomics analysis tool based on the ψ (DNMT2-ALYREF-ALKBH1-KMTs-spacer C9) modification and Mevalonate pathway-mediated (hnRNPs-SAM-NAD+) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
KMTs
RNA types
rRNA
Modification
ψ
Label
spacer C9
RNA editing
T to C
Cell Type
MDSCs
Oligonucleotide
cET, 2'-MOE
RNA Construction
rRNA-ψ-DNMT2-ALYREF-ALKBH1-KMTs-spacer C9
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
P300/CBP overexpression
Metabolic alteration
Upregulating glycolysis and amino acidsmetabolism
Targeting diseases
Pancreatic Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-SAM-NAD+
Target
OTC
Alternative Names
OTC; OCTD; ornithine carbamoyltransferase; ornithine transcarbamylase; OTCD
Gene ID
5009(Human); 18416(Mouse); 25611(Rat)
UniProt ID
P00480(Human); P11725(Mouse); P00481(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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