ALP-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR238
Cell Type: M2 macrophages
RNA writers: TRMT6/61A
RNA readers: YTHDF1/2/3
RNA erasers: ALKBH7
Enzymes: NMNAT1
RNA types: mRNAs
Modification: m7G
RNA editing: A to I
Short Description
This product is a ALP-targeted RNA modification and metabolomics analysis tool based on the m7G (TRMT6/61A-YTHDF1/2/3-ALKBH7-NMNAT1-phos) modification and Glycolysis-mediated (nELAVL-SAM-ADP) metabolic analysis system.
RNA writers
TRMT6/61A
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH7
Enzymes
NMNAT1
RNA types
mRNAs
Modification
m7G
Label
phos
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m7G-TRMT6/61A-YTHDF1/2/3-ALKBH7-NMNAT1-phos
Substrates
SAM
Cofactors
ADP
Pathway
Glycolysis
Epigenetic regulator
HDAC11 overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
nELAVL
Metabolic Reprogramming
Glycolysis-nELAVL-SAM-ADP
Target
ALP
Alternative Names
Alkaline phosphatase; ALP
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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