BCKA-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR359
Cell Type: DCs
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: NAMPT
RNA types: tRNA
Modification: ac4C
RNA editing: G to A
Short Description
This product is a BCKA-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-NAMPT-spacer C9) modification and Fatty acid synthesis-mediated (TDP-43-Succinyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
NAMPT
RNA types
tRNA
Modification
ac4C
Label
spacer C9
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
LNA
RNA Construction
tRNA-ac4C-METTL3-YTHDF1-FTO-NAMPT-spacer C9
Substrates
Succinyl-CoA
Cofactors
ADP
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Pancreatic Cancer
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Fatty acid synthesis-TDP-43-Succinyl-CoA-ADP
Target
BCKA
Alternative Names
BCKA; branched-chain α-keto acid decarboxylase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.