BCKDH-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR366
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: MAT2A
RNA types: rRNA
Modification: ac4C
RNA editing: A to I
Short Description
This product is a BCKDH-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-MAT2A-phos) modification and Fatty acid synthesis-mediated (hnRNPs-SAM-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
MAT2A
RNA types
rRNA
Modification
ac4C
Label
phos
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
rRNA-ac4C-METTL3-YTHDF1-FTO-MAT2A-phos
Substrates
SAM
Cofactors
NAD+
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Glioblastoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Fatty acid synthesis-hnRNPs-SAM-NAD+
Target
BCKDH
Alternative Names
BCKDH; Branched-chain alpha-keto acid dehydrogenase complex
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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