BiliTrack™ High-Sensitivity Human Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) ELISA Kit

CAT#: ITS-0326-WB151
Product Type: ELISA Kit
Species: Human
Target: Human tissue-nonspecific alkaline phosphatase (ALPL)
Brand: BiliTrack™
Development Stage: ADME
ADME Research Domain: Excretion
Short Description
Ultra-sensitive quantification of human ALPL in biological samples using advanced sandwich ELISA technology.
Brand
BiliTrack™
Development Stage
ADME
ADME Research Domain
Excretion
Description
BiliTrack™ High-Sensitivity Human Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) ELISA Kit delivers precise and ultra-sensitive detection of ALPL across human sample types. Leveraging an optimized sandwich ELISA platform, it enables reliable quantification of low-abundance ALPL in serum, plasma, and tissue lysates, supporting advanced research in bone, liver, and metabolic disorders.
Features
Ultra-sensitive detection capability enables accurate quantification of very low ALPL concentrations in complex biological samples with minimal signal interference.
Highly specific antibody pairing ensures selective recognition of tissue-nonspecific ALPL isozyme across liver, bone, and kidney-derived samples.
Optimized assay components and standardized protocol provide excellent reproducibility and consistent performance across independent experimental runs.
Broad compatibility with multiple human sample types enhances flexibility for clinical research and biomarker-driven studies.
Process Relevance
Detects subtle ALPL changes to support precise monitoring of metabolic and disease-related enzymatic activity.
Application Stage
Clinical research, early biomarker discovery, and high-sensitivity translational studies.
Applications
High-sensitivity quantification of ALPL in human serum, plasma, and tissues; detection of low-level biomarkers; bone and liver disease studies; ADME profiling studies; enzymatic activity profiling; clinical sample analysis.
Target
Human tissue-nonspecific alkaline phosphatase (ALPL)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Clinical diagnostics, bone metabolism, hepatology, nephrology, enzymology, pharmacokinetics (ADME), metabolic disease research, etc.
Size
96 tests
Data Output Type
Ultra-sensitive quantitative measurement of ALPL protein levels via colorimetric ELISA detection.
Assay Range
78.1 pg/ml - 5000 pg/ml
LOD
46.9 pg/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Tissue-nonspecific alkaline phosphatase (ALPL) is a key enzyme expressed in liver, bone, and kidney, regulating phosphate metabolism and mineralization. Its activity reflects physiological and pathological states. Subtle variations in ALPL levels are critical indicators in early-stage disease detection and metabolic dysregulation.
Pathways
ALPL is central to phosphate metabolism and biomineralization pathways, promoting hydroxyapatite formation in bone. It functions downstream of osteoblast differentiation signals and contributes to hepatobiliary and renal metabolic regulation. Its activity influences extracellular matrix stability and systemic phosphate homeostasis.
For Research Use Only | Not For Clinical Use
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