CD38 Assay Portfolio Service

Tumor Target CD38

CD38 is expressed on several hematological malignancies and tumor-related immunosuppressive cells, including regulatory T cells, regulatory B cells, and bone marrow-derived suppressor cells. CD38 possesses multiple functions, such as enzyme activity, adhesion effects, and plays a vital role in normal cell functions and tumor growth. CD38 has important enzymatic functions, interacting with the substrate ligands NAD and NADP, which can be transformed into cADPR, ADPR, and NAADP. As a receptor for ligand CD31 and hyaluronic acid, CD38 mediates cell proliferation, adhesion, and T-cell activation.

What We Can Offer

In Vitro Assays	In Vivo Assays
CD38-targeted Leads Screening Binding Affinity Test Epitope Mapping Functional Assay	Model Construction: Create relevant disease models for your research. PK/PD Study: Analyze the drug's behavior and its biological effects within a living system.

Highlights

Unmatched Scientific Expertise

Our deep understanding of CD38 biology, coupled with extensive experience in immunology, oncology, and assay development, ensures intelligent experimental design and insightful data interpretation for your complex projects.

State-of-the-Art Technology & Comprehensive Solutions

Our comprehensive suite of assay modalities, from in vitro functional assays to in vivo PK/PD studies and custom assay development, provides a holistic approach to characterizing your therapeutic candidates.

Proven Track Record of Client Success

Our commitment to excellence translates into tangible benefits for our clients. On average, clients experience a 30% increase in therapeutic candidate characterization efficiency and a 25% reduction in assay development timelines when partnering with Creative Biolabs.

Collaborative Partnership & Rigorous Quality Assurance

We believe in a truly collaborative approach, working as an extension of your R&D team to tailor solutions to your specific research goals. Our services adhere to stringent quality control standards, ensuring every result is accurate, reproducible, and robust.

Experience the Creative Biolabs advantage - Get a quote today.

Customer Reviews

Exceptional Data Quality
Using Creative Biolabs' service in our research has significantly improved the reliability of our lead compound selection. Their enzymatic activity assays provided precise IC50 values that were crucial for our SAR studies, far surpassing the consistency we achieved in-house. - J***n S.

Streamlined Workflow
Creative Biolabs' service greatly facilitated our antibody characterization. Their ADCC and CDC assays provided clear insights into our therapeutic antibody's mechanism of action, saving us critical time compared to setting up these complex assays ourselves. - M***a K.

FAQs

What types of CD38-targeting agents can Creative Biolabs' assays characterize?

Our comprehensive portfolio is equipped to characterize a wide range of agents, including monoclonal antibodies, antibody-drug conjugates, bispecific antibodies, and various small-molecule inhibitors. We tailor our assays to the specific properties of your therapeutic candidate.

How does Creative Biolabs ensure the accuracy and reproducibility of its CD38 assay results?

We adhere to stringent quality control standards, employing validated protocols, state-of-the-art instrumentation, and highly skilled scientists. Each assay undergoes rigorous optimization, and data analysis is performed using validated software, ensuring the highest levels of accuracy and reproducibility for your research.

Can Creative Biolabs assist with custom CD38 assay development for unique research questions?

Absolutely! Our team excels in custom assay development. If your project requires a specialized approach, we will collaborate closely with you to design, optimize, and validate bespoke assays, addressing complex biological questions such as the role of CD38 subcellular localization or specific enzymatic activities.

Related Services

Antibody Discovery

We focus on developing diverse antibody repertoires with high specificity and affinity, ensuring optimal therapeutic potential and manufacturability for your drug candidates.

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Cell Line Development

We specialize in developing reporter cell lines, overexpression cell lines, and disease-specific models, ensuring consistent and reproducible results that are essential for robust drug discovery and development.