Development Stage: Research-Grade Cellular Function Assay Development
Short Description
Measures glucose uptake in cultured cells using a fluorescent analog.
Brand
CelluTest
Development Stage
Research-Grade Cellular Function Assay Development
Description
The CelluTest™ Glucose Uptake Assay Kit utilizes a non-radioactive fluorescent analog for the high-throughput screening of insulin mimetics and glucose transporter modulators. This assay validates the efficacy of anti-diabetic drugs by measuring glucose entry into cells. It provides a safe and sensitive alternative to radiolabeled assays for functional studies of glucose transport.
Features
Non-radioactive fluorescent analog; High-throughput screening of insulin mimetics and glucose transporter modulators.
Process Relevance
Insulin Sensitivity Screening
Application Stage
Hit-to-Lead Screening
Applications
Insulin signaling and diabetes drug discovery.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Cell culture
Research Areas
Diabetes & Obesity
Size
100 tests
Data Output Type
Quantitative (Fluorescence Intensity)
Assay Time
Results in 2 hr
LOD
0.1 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glucose uptake is the rate-limiting step for utilization. Impaired uptake is the hallmark of insulin resistance. Fluorescent analogs allow for high-throughput screening of insulin sensitizers.