Development Stage: Research-Grade Cellular Function Assay Development
Short Description
Measures LDH activity, a marker of tissue damage.
Brand
CelluTest
Development Stage
Research-Grade Cellular Function Assay Development
Description
The CelluTest™ Lactate Dehydrogenase Kit serves as a standard non-radioactive endpoint for measuring cell death and membrane integrity in ADME/Tox screening. This assay is ubiquitous in pharmaceutical research for assessing the cytotoxicity of drug candidates. It offers a rapid, reliable metric for tissue damage in both in vitro cell culture and in vivo serum analysis.
Features
Non-radioactive cytotoxicity assay; Standard endpoint for measuring cell death in ADME/Tox screening.
Process Relevance
General Cytotoxicity Screening
Application Stage
ADME / Toxicology
Applications
General cytotoxicity marker and tissue damage assessment.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, plasma samples
Research Areas
Toxicology; Cell Biology
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30 min
LOD
2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Lactate Dehydrogenase (LDH) converts lactate to pyruvate. Present in almost all tissues its release into the extracellular space is a non-specific but sensitive marker of cell death and tissue injury.