CytoFinal™ Monkey Alanine Aminotransferase 1 / ALT (GPT) ELISA Kit

CAT#: ITS-0326-WB74
Product Type: ELISA Kit
Species: Monkey
Target: Monkey alanine aminotransferase 1 (ALT1/GPT)
Brand: CytoFinal™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Sensitive ELISA kit for quantifying ALT1 (GPT) protein levels in monkey biological samples.
Brand
CytoFinal™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
CytoFinal™ Monkey Alanine Aminotransferase 1 / ALT (GPT) ELISA Kit provides a reliable immunoassay for measuring ALT1 protein in monkey serum, plasma, tissue lysates, and cultured cells. Using a sandwich ELISA format with highly specific antibodies, the kit enables accurate quantification of ALT, supporting preclinical liver injury studies, metabolic research, and translational toxicology investigations.
Features
High-affinity monkey-specific antibody pair ensures selective detection of ALT1 with minimal cross-reactivity to related aminotransferase isoforms.
Sensitive sandwich ELISA design allows precise measurement of low-abundance ALT protein in complex biological matrices.
96-well microplate format facilitates efficient high-throughput analysis compatible with standard ELISA readers.
Optimized reagents and calibrated standards provide reproducible, quantitative results across multiple experimental runs.
Process Relevance
Quantifies ALT protein to monitor hepatocellular injury and metabolic enzyme alterations in preclinical monkey models.
Application Stage
Preclinical studies, toxicology evaluation, translational metabolism research, and biomarker analysis.
Applications
Measurement of ALT protein in monkey serum, plasma, tissue lysates, and cultured cells for liver injury assessment, metabolic pathway studies, ADME profiling studies, and toxicology biomarker research.
Target
Monkey alanine aminotransferase 1 (ALT1/GPT)
Detection Method
Colorimetric
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Hepatology, toxicology, metabolic disease research, pharmacology, pharmacokinetics (ADME), translational biomedical research, preclinical metabolism studies, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration determined from absorbance signals generated by sandwich ELISA detection.
Assay Range
0.156 ng/ml - 10 ng/ml
LOD
< 0.056 ng/ml
Species
Monkey
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
ALT1 catalyzes the reversible transfer of an amino group between alanine and α-ketoglutarate, producing pyruvate and glutamate. In monkeys, ALT levels serve as reliable biomarkers for liver injury, metabolic dysfunction, and preclinical toxicology studies.
Pathways
ALT1 participates in the alanine cycle, linking peripheral amino acid metabolism to hepatic gluconeogenesis. Produced pyruvate can enter the TCA cycle or gluconeogenic pathways, integrating nitrogen metabolism with cellular energy production.
For Research Use Only | Not For Clinical Use
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