Creative Biolabs-Immuno-oncology

E4P-targeted RNA Modification and Metabolomics Analysis Tool (CAT#: ITS-0524-CR108)

DatasheetDatasheet
Short Description
This product is a E4P-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-YTHDF2-ALKBH5-HDACs-spacer C9) modification and Mevalonate pathway-mediated (α-synuclein-Lactyl-CoA-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
rRNA
Modification
ψ
Label
spacer C9
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
rRNA-ψ-METTL14-YTHDF2-ALKBH5-HDACs-spacer C9
Substrates
Lactyl-CoA
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-Lactyl-CoA-NAD+
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For Research Use Only | Not For Clinical Use

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