Short Description
This product is a E4P-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-YTHDF2-ALKBH5-HDACs-spacer C9) modification and Mevalonate pathway-mediated (α-synuclein-Lactyl-CoA-NAD+) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
rRNA-ψ-METTL14-YTHDF2-ALKBH5-HDACs-spacer C9
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-Lactyl-CoA-NAD+