Short Decsription
Endotoxin assay kit for water and dialysate assays the endotoxin in water or dialysate by using gel clot technique.
Description
Endotoxin assay kit for water and dialysate assays the endotoxin in water or dialysate by using gel clot technique.
Features
Endotoxin assay kit for water and dialysate contains endotoxin-specific amebocyte lysate, which will only react with endotoxin and will avoid false positive reaction with Fungi (1-3)-β-D-Glucan in the dialysis membrane.
Applications
Endotoxin detection
Molecular Mechanism of Action
LAL test relys on factor C coagulation cascade found in horseshoe crabs' blood. The combination of endotoxin and zymogen factor C initiate the protease cascade. Next, the activated factor C goes onto activate factor B, which converts the proclotting enzyme to the clotting enzyme. Lastly, two peptide bonds in coagulogen are catalytically cleaved to form coagulin gel.
Qualified With
Quality certificate
Method Type
Lyophilized amebocyte lysate (LAL)
Datasheet