Creative Biolabs-Immuno-oncology

Genomic based Metastatic Tumor Microbiome Analysis Service

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Are you currently facing challenges in understanding complex cancer progression, identifying novel therapeutic targets, or developing precise diagnostic biomarkers for metastatic disease? Creative Biolabs' genomic based metastatic tumor microbiome analysis service helps you unlock the intricate interplay between the tumor microbiome and metastasis, accelerating your research and development through advanced multi-omics sequencing technologies. We provide comprehensive insights into microbial signatures, their impact on the tumor microenvironment, and their potential as prognostic and therapeutic targets.

Introduction

The tumor microbiome, once considered a mere bystander, is now recognized as a critical "permanent resident" profoundly influencing the trajectory of cancer, from initiation and progression to therapeutic response. The breakthroughs in next-generation sequencing and multi-omics technologies made it possible to unravel the intricate interactions between host and microbial genomes. This understanding is pivotal for developing advanced diagnostics and precision therapies, especially for metastatic disease, where the role of microbiome in influencing outcomes and treatment efficacy is increasingly evident.

Fig.1 Exploring the role of microbiome in cancer progression through multi-omics approaches. (OA Literature)Fig.1 The multi‐omics methods to explore the role of microbiome in tumor development.1

Genomic-based Metastatic Tumor Microbiome Analysis Service at Creative Biolabs

Creative Biolabs' genomic based metastatic tumor microbiome analysis service provides an unprecedented level of clarity regarding the microbial communities residing within metastatic tumor lesions. Furthermore, we provide tailored methodologies specifically designed for discerning microbial biomarkers, unraveling the intricate mechanisms underpinning metastasis, and delineating novel therapeutic targets. Our service aims to facilitate a profound comprehension of the complex involvement of endogenous tumor-associated microbiota and their circulating counterparts in neoplastic advancement and therapeutic efficacy, thereby fostering the development of highly refined diagnostic modalities and targeted therapeutic interventions.

What We Can Offer?

Our Service Process

We employ high-precision sequencing methodologies to enhance the analysis of low-abundance tumor microbial genomes, thereby enriching the data with greater completeness and significance, helping you develop of more effective therapeutic strategies. Our comprehensive workflow is meticulously designed, from sample preparation to final data interpretation, to help you explore the important role of microbiome in metastatic tumor.

Flowchart of genomic based metastatic tumor microbiome analysis service. (Creative Biolabs Original)

Key Advantages

FAQs

Q1: What types of samples can I submit for Genomic based Metastatic Tumor Microbiome Analysis?

A1: We recommend fresh-frozen or high-quality FFPE from metastatic tumor tissue samples and liquid biopsy samples such as plasma or serum. Moreover, it is meaningful to provide matched normal tissue or pre-treatment liquid biopsy to maximize analytical precision and reproducibility. If you have unique sample types, please contact us to for bespoke qualification protocols

Q2: How does Creative Biolabs' service differentiate between host and microbial DNA in tumor samples?

A2: Our advanced bioinformatics pipelines incorporate rigorous host depletion strategies. Through leveraging comprehensive reference databases and sophisticated computational algorithms, we distinguish microbial sequences from host genetic material and provide a precise and reliable microbial profile.

Q3: Can this service help identify biomarkers for predicting immunotherapy response in metastatic cancer?

A3: Absolutely. Our Genomic based Metastatic Tumor Microbiome Analysis service is designed to identify specific microbial signatures and host-microbe interaction patterns, which is useful for you to find novel predictive biomarkers and develop personalized treatment strategies.

Why Choose Us?

Choosing Creative Biolabs for your Genomic based Metastatic Tumor Microbiome Analysis needs means partnering with a leader in advanced biological research. Our distinct advantage lies in our unparalleled expertise, cutting-edge multi-omics platforms, and unwavering commitment to delivering actionable and insightful outcomes that drive scientific advancement and innovation.

Customer Reviews

"Using Creative Biolabs' Genomic based Metastatic Tumor Microbiome Analysis Service in our research has significantly improved our understanding of the microbial landscape within metastatic lesions. The depth of data allowed us to identify subtle yet critical microbial shifts that were previously undetectable, directly informing our biomarker development efforts. "–14 weeks, Dr. J. S***th

"Creative Biolabs' multi-omics integration capabilities are truly exceptional. Their service facilitated the rapid correlation of microbial profiles with host gene expression, accelerating our discovery of novel therapeutic targets in pancreatic cancer and saving us months of independent analysis. " –10 weeks, Prof. A. R***s

" [Reliable & Actionable Data] The precision and reliability of the data from Creative Biolabs' service are outstanding. We were particularly impressed by their ability to handle low-biomass samples, providing actionable insights into rare microbial populations that are crucial for early detection strategies. This service is a game-changer for precision oncology. "–16 weeks, Dr. L. M***n

Contact us for more information and to discuss your project.

Reference

  1. Zhang, Nan et al. "Applying multi-omics toward tumor microbiome research." iMeta vol. 2,1 e73. 9 Jan. 2023, doi:10.1002/imt2.73. Distributed under Open Access License CC BY 4.0, without modification. DOI: https://doi.org/10.1002/imt2.73

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