GOT2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR55
Cell Type: DCs
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: D2HGDH
RNA types: mRNAs
Modification: m1A
RNA editing: C to U
Short Description
This product is a GOT2-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL3-YTHDF1-FTO-D2HGDH-spacer C9) modification and Mevalonate pathway-mediated (MBNL-SAM-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
D2HGDH
RNA types
mRNAs
Modification
m1A
Label
spacer C9
RNA editing
C to U
Cell Type
DCs
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
mRNAs-m1A-METTL3-YTHDF1-FTO-D2HGDH-spacer C9
Substrates
SAM
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Glioma
RNA-binding proteins
MBNL
Metabolic Reprogramming
Mevalonate pathway-MBNL-SAM-α-KG
Target
GOT2
Alternative Names
GOT2; KAT4; KATIV; mitAAT; KYAT4; glutamic-oxaloacetic transaminase 2; DEE82
Gene ID
2806(Human); 14719(Mouse); 25721(Rat)
UniProt ID
P00505(Human); P05202(Mouse); P00507(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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