TKL-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR69
Cell Type: M1 macrophages
RNA writers: TRMT10C
RNA readers: YTHDC1
RNA erasers: ALKBH3
Enzymes: ACL
RNA types: rRNA
Modification: m1A
RNA editing: C to U
Short Description
This product is a TKL-targeted RNA modification and metabolomics analysis tool based on the m1A (TRMT10C-YTHDC1-ALKBH3-ACL-phos) modification and Glycolysis-mediated (HTT-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
TRMT10C
RNA readers
YTHDC1
RNA erasers
ALKBH3
Enzymes
ACL
RNA types
rRNA
Modification
m1A
Label
phos
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
LNA
RNA Construction
rRNA-m1A-TRMT10C-YTHDC1-ALKBH3-ACL-phos
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Glycolysis
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Gastric Cancers
RNA-binding proteins
HTT
Metabolic Reprogramming
Glycolysis-HTT-Acetyl-CoA-α-KG
Target
TKL
Alternative Names
TKL; transketolase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.