HMT-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR214
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: MDH2
RNA types: mRNAs
Modification: m6Am
RNA editing: A to I
Short Description
This product is a HMT-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDF1-FTO-MDH2-phos) modification and Mevalonate pathway-mediated (hnRNPs-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
MDH2
RNA types
mRNAs
Modification
m6Am
Label
phos
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m6Am-METTL3-YTHDF1-FTO-MDH2-phos
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Colorectal Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-SAM-ADP
Target
HMT
Alternative Names
Histone methyltransferases (HMT
Gene ID
3176(Human); 140483(Mouse); 81676(Rat)
UniProt ID
P50135(Human); Q91VF2(Mouse); Q01984(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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