PharmaOnco™ C6-Tg(Rat BB1 Receptor) Stable Cell Line, Single Clone

CAT#: ITS-0624-HMM49
Product Type: Stable Cell Line
Short Description
Creative Biolabs offers C6-Tg(Rat BB1 Receptor) Stable Cell Line which BB1 receptor stably expressed in C6 cells.
Description
C6-Tg(Rat BB1 Receptor) Stable Cell Line was engineered to express the receptor rat BB1 (NM_012799). The BB1 receptor is involved in the physiological effects of bradykinin. This cell line can be used to study BB1 receptor function, signaling pathways, and potential therapeutic interventions.
Features
Minimally modified GPCRs directly selected in functional assays;
Strict quality control;
Parental and orthologous cell lines are available.
Applications
BB1 receptor function, signaling pathways, and potential therapeutic interventions.
Protein Target
GPCR
Receptor Name
BB1
Receptor Family
Bombesin
Species
Rat
Parental Cell Line
C6
Transfection
Full-length rat NMBR cDNA with flag tag sequence at N-terminus
Gene
NM_012799
Background
The BB1 receptor, also known as B1 receptor, is a subtype of bradykinin receptors, which are part of the G protein-coupled receptor (GPCR) family. These receptors are primarily activated by bradykinin, a peptide involved in various physiological processes such as inflammation, pain modulation, and vascular permeability regulation.
Unit Size
2 x 10e6 cells/vial, Frozen
Culture Medium
DMEM, 10% FBS
Frozen Formulation
Cell freezing medium
Cell Purity
>95%
Cell Viability
>90%
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Identity Testing
Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.
Virological Safety Testing
A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Shipping
Dry Ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Quality Control
All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.
For Research Use Only | Not For Clinical Use
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