PharmaOnco™ CHO-Tg(Human CD70) Stable Cell Line, Single Clone

Creative Biolabs offers CHO-Tg(Human CD70) stable cell line which the CD70 gene stably expressed in CHO cells.

CHO-Tg(Human CD70) stable cell line is a genetically modified Chinese hamster ovary (CHO) cell line that has been transfected with the gene encoding the human CD70 protein. CD70 is a type II transmembrane glycoprotein that belongs to the tumor necrosis factor (TNF) receptor superfamily. It is primarily expressed on the surface of activated T cells and plays a critical role in regulating immune responses. The stable expression of human CD70 in CHO cells allows for the production of recombinant CD70 protein in large quantities for research purposes, such as studying its functions in immune signaling pathways or developing CD70-targeted therapies for cancer and autoimmune diseases.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

CD70

Human

CHO

The CD70 gene encodes a protein known as CD70, which is a cell surface receptor molecule that is part of the tumor necrosis factor receptor superfamily. CD70 is primarily expressed on activated immune cells, such as T cells and B cells, and plays a role in regulating immune responses. CD70 is involved in activating immune cells, promoting T cell proliferation and differentiation, and modulating the immune response. It has been implicated in various immune-related diseases, including autoimmune diseases, cancer, and infectious diseases.

1 x 10e6 cells/vial, Frozen

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.

A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Dry Ice

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Avoid multiple freeze/thaw cycles

For research use only, not for diagnostic or therapeutic use.

All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.