PharmaOnco™ CTLA4 / IL-2 Reporter - Jurkat Recombinant Cell Line (Human) (CAT#: IOC-02P066)

Recombinant Jurkat T cell expressing firefly luciferase gene under the control of IL-2 promoter with constitutive expression of human CTLA4 (Cytotoxic T-Lymphocyte Associated Protein, CD152; GenBank Accession #NM_005214).

Screen for activators or inhibitors of CTLA4 signaling in a cellular context
Characterize the biological activity of CTLA4 and its interactions with ligands

Human

JURKAT

CD152

Lymphoid Tissue