PharmaOnco™ Human Treg Cells, Induced

Creative Biolabs offers Human Treg Cells, Induced for suppressing lymphocyte function and some function assay.

Human regulatory T cells (Tregs) are a subset of T cells that play a crucial role in maintaining immune tolerance and preventing autoimmunity. Tregs can be induced from conventional T cells in the presence of specific cytokines and signals. Induced Tregs have been shown to exhibit similar suppressive function as natural Tregs, and they have been explored as a potential therapeutic strategy for treating autoimmune diseases and transplant rejection.

Regulatory T cells (Tregs) are a subset of T cells that play a crucial role in maintaining immune tolerance and preventing autoimmunity. They have anti-inflammatory properties and can suppress the immune response to prevent excessive inflammation. Human Tregs can be induced from conventional T cells (Tconvs) in various ways. One common method is through the use of cytokines such as TGF-β and IL-2, which promote the differentiation of Tconvs into Tregs. Other methods include the use of specific antibodies or small molecules that target signaling pathways involved in Treg development. Induced Tregs have been studied in various disease models, including autoimmune diseases, transplant rejection, and cancer. They have shown promising results in suppressing inflammation and promoting immune tolerance in these conditions.

Human

T cells

CD4 T Cells

PRMI1640

High quality;
High viability;
Widely applications.

Healthy

Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).

Contains Cryopreservation Medium

> 80%

> 80%

Negative

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

All cells were collected under Institutional Review Board (IRB)-approved consent forms and protocols.

Immunotherapy Discovery and Development

Donors are negative for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Stored at < -120°C once they are received.

Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.

Avoid multiple freeze/thaw cycles.

1 x 10e6 cells/vial

Frozen

Certain products are only available in select territories. Please contact us for more information.