BIGaxis™ Isolation, Culture, and Characterization Service of Neurons

As the fundamental unit of the nervous systems, neurons are responsible for receiving internal and external sensory input and implementing our complex bodily functions and behaviors. They can be classified in many ways including structure, function, connection, electrical properties, and neurotransmitter expression. Creative Biolabs offers isolation, culture, and characterization service of neurons to facilitate your microbe project's success.

Neurons

Neuron is an electrically excitable cell that communicates with other cells via specialized connections. The typical neuron generally consists of a cell body, dendrites, and a single axon (shown in Fig.1). The cell body is a compact structure and the axon and dendrites are filaments extruding from the cell body. Dendrites typically branch profusely and extend a few hundred micrometers from the cell body, and the axon leaves the soma at a swelling called the axon hillock. In most instances, neurons are generated by neural stem cells during brain development and childhood. Neurogenesis largely ceases during adulthood in most areas of the brain.

Classification of Neurons

TYPE	DETAILED CONTENT
Structural classification	Polarity Unipolar, Bipolar, Multipolar (Golgi I and Golgi II), Anaxonic, Pseudounipolar. Other Basket cells, Betz cells, Lugaro cells, Medium spiny neurons, Purkinje cells, Pyramidal cells, Renshaw cells, Unipolar brush cells, Granule cells, Anterior horn cells, Spindle cells.
Functional classification	Direction Afferent neurons, Efferent neurons, Interneurons. Action on other neurons Excitatory, Inhibitory, Modulatory. Discharge patterns Tonic or regular spiking, Phasic or bursting, Fast spiking. Neurotransmitter Multimodel classification

Our Service

Cell Isolation
Creative Biolabs offers high-quality services of rapid isolation of untouched neurons from neonatal and adult mouse brain. The untouched neurons can be purified with the neuron isolation kit. The procedure of isolation is simple and fast. It takes only one hour to acquire highly purified and viable neurons from a single cell suspension.
Cell Culture
Cultivation of primary adult mouse neurons can be a challenging task. Creative Biolabs offers cell culture services to cultivate neurons from mouse samples. Our serum-free neuro medium improves the performance of your neuron culture.
Cell Characterization
Creative Biolabs offers specific approaches to characterize the neurons:

Immunofluorescence staining and microscopy
Flow cytometry
Single-cell sequencing

Highlights

Modular neuronal cell workflows
High purity of untouched isolated cells
Serum-free and feeder layer-free system

Creative Biolabs offers a comprehensive range of solutions for isolation, culture, and characterization service of neurons. More solutions to brain-immune-gut research can be found in the unit of our Brain-Immune-Gut interaction Study. If you have any questions about your microbe project, please feel free to contact us.

Download our brochure

Loading case studies...

Online Inquiry