MetaVital™ Human Glutathione S Transferase Alpha 1 (GSTa1) ELISA Kit

CAT#: ITS-0326-WB34
Product Type: ELISA Kit
Species: Human
Target: Human Glutathione S Transferase Alpha 1 (GSTa1) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively detects human GSTa1 levels in biological samples for detoxification and oxidative stress studies.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human Glutathione S Transferase Alpha 1 (GSTa1) ELISA Kit provides a sensitive and reliable assay for quantifying GSTa1 in human serum, plasma, and tissue extracts. This kit supports studies of xenobiotic metabolism, hepatic injury biomarkers, and oxidative stress mechanisms, offering consistent performance for pharmacological and toxicological investigations.
Features
Highly specific antibody pair enables accurate recognition of human GSTa1 while minimizing cross-reactivity with other glutathione S-transferase isoenzymes.
Sensitive colorimetric ELISA detection system supports reliable quantification across a broad concentration range in complex biological matrices.
Pre-coated microplate with calibrated standards and optimized reagents simplifies workflow and improves inter-assay reproducibility.
Robust assay configuration supports efficient processing of multiple samples while maintaining stable signal output and dependable analytical performance.
Process Relevance
Enables monitoring of GSTa1 levels to assess hepatic detoxification activity and oxidative stress responses.
Application Stage
Drug discovery, clinical biomarker research, toxicology studies, and metabolic pathway analysis.
Applications
Quantitative ELISA measurement of GSTa1 in human serum, plasma, and tissue lysates for studies of liver injury biomarkers, oxidative stress responses, ADME profiling, and xenobiotic metabolism.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Human Glutathione S Transferase Alpha 1 (GSTa1) protein
Detection Method
Colorimetric
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, pharmacokinetics (ADME), toxicology, oxidative stress biology, hepatology research, pharmacology, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using a colorimetric endpoint ELISA assay.
Assay Range
0.31 ng/ml - 20 ng/ml
LOD
0.19 ng/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferase Alpha 1 (GSTa1) is a key cytosolic detoxification enzyme predominantly expressed in liver cells. It catalyzes the conjugation of glutathione to reactive electrophilic compounds, protecting cells from oxidative damage and chemical toxicity.
Pathways
GSTa1 functions within the glutathione-mediated phase II detoxification pathway. It catalyzes conjugation reactions that neutralize reactive metabolites produced during xenobiotic metabolism, facilitating detoxification and maintaining cellular redox balance.
For Research Use Only | Not For Clinical Use
Online Inquiry