ModifiSite™ Asparaginase Assay Kit

CAT#: ITS-1125-HM102
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Quantifies asparaginase activity via aspartate detection.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Asparaginase Assay Kit offers aspartate-specific detection for the pharmacodynamic monitoring of L-asparaginase levels during leukemia treatment. This assay validates the enzymatic activity of therapeutic preparations, ensuring optimal dosing in oncology. It supports the development of novel asparaginase formulations with improved stability and reduced immunogenicity.
Features
Aspartate specific detection; Pharmacodynamic monitoring of L-asparaginase levels in leukemia treatment.
Process Relevance
Biologic Drug Monitoring (TDM)
Application Stage
Clinical Pharmacology
Applications
Monitoring L-asparaginase therapy in leukemia.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 415 nm / Em 475 nm)
Sample Type
Serum, Plasma, urine, and other biological samples
Research Areas
Oncology; Pharmacology
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 40 min
LOD
1.1 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
L-Asparaginase is a chemotherapeutic enzyme used to treat leukemia by depleting circulating asparagine. Monitoring its activity ensures therapeutic levels are maintained and detects neutralizing antibodies.
For Research Use Only | Not For Clinical Use
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