Short Description
Quantifies asparaginase activity via aspartate detection.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Asparaginase Assay Kit offers aspartate-specific detection for the pharmacodynamic monitoring of L-asparaginase levels during leukemia treatment. This assay validates the enzymatic activity of therapeutic preparations, ensuring optimal dosing in oncology. It supports the development of novel asparaginase formulations with improved stability and reduced immunogenicity.
Features
Aspartate specific detection; Pharmacodynamic monitoring of L-asparaginase levels in leukemia treatment.
Process Relevance
Biologic Drug Monitoring (TDM)
Application Stage
Clinical Pharmacology
Applications
Monitoring L-asparaginase therapy in leukemia.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 415 nm / Em 475 nm)
Sample Type
Serum, Plasma, urine, and other biological samples
Research Areas
Oncology; Pharmacology
Datasheet