ModifiSite™ β-Glucosidase Assay Kit

CAT#: ITS-1125-HM59
Product Type: Assay Kit
Species: All Species
Short Description
Determines beta-glucosidase activity in biological samples.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ β-Glucosidase Assay Kit offers a simple, robust method for measuring enzyme activity, critical for screening chaperone therapies for Gaucher disease. This assay validates the efficacy of treatments designed to restore lysosomal function and hydrolyze glucosylceramide. It is also applicable in biofuel research for evaluating the efficiency of cellulolytic enzyme cocktails.
Features
Simple mix-and-read protocol; Validates chaperone therapies for Gaucher disease and enzyme replacement efficacy.
Process Relevance
Rare Disease Therapy (Gaucher)
Application Stage
Therapeutic Efficacy Testing
Applications
Gaucher disease screening and biofuel research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Lysosomal Storage Disorders (Gaucher)
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 20 min
LOD
2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Beta-Glucosidase hydrolyzes beta-glucosidic bonds in carbohydrates. It is the enzyme deficient in Gaucher disease leading to glucosylceramide accumulation; measuring its activity is crucial for diagnosis.
For Research Use Only | Not For Clinical Use
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