Short Description
Determines beta-glucosidase activity in biological samples.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ β-Glucosidase Assay Kit offers a simple, robust method for measuring enzyme activity, critical for screening chaperone therapies for Gaucher disease. This assay validates the efficacy of treatments designed to restore lysosomal function and hydrolyze glucosylceramide. It is also applicable in biofuel research for evaluating the efficiency of cellulolytic enzyme cocktails.
Features
Simple mix-and-read protocol; Validates chaperone therapies for Gaucher disease and enzyme replacement efficacy.
Process Relevance
Rare Disease Therapy (Gaucher)
Application Stage
Therapeutic Efficacy Testing
Applications
Gaucher disease screening and biofuel research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Lysosomal Storage Disorders (Gaucher)
Datasheet