ModifiSite™ α-Mannosidase Assay Kit

CAT#: ITS-1125-HM138
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Quantifies alpha-mannosidase activity.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ α-Mannosidase Assay Kit utilizes specific substrate cleavage to screen for alpha-mannosidosis and assess lysosomal function. This assay supports the diagnosis of glycoprotein storage disorders and the monitoring of enzyme replacement therapies. It validates the activity of alpha-mannosidase in leukocytes and tissue samples.
Features
Specific substrate cleavage; Screening for alpha-mannosidosis and lysosomal function.
Process Relevance
Lysosomal Function Research
Application Stage
Diagnosis / Research
Applications
Lysosomal storage disease (Mannosidosis) screening.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Lysosomal Storage Disorders
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 10 min
LOD
1 U/L
Species
All Species
Storage
Store at 4 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid freezing unless otherwise specified. During use, minimize prolonged exposure to room temperature and return components promptly to 2-8 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Alpha-Mannosidase is a lysosomal enzyme involved in glycoprotein degradation. Deficiency leads to Alpha-Mannosidosis a storage disorder characterized by immune deficiency and skeletal abnormalities.
For Research Use Only | Not For Clinical Use
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