Short Description
Quantifies alpha-mannosidase activity.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ α-Mannosidase Assay Kit utilizes specific substrate cleavage to screen for alpha-mannosidosis and assess lysosomal function. This assay supports the diagnosis of glycoprotein storage disorders and the monitoring of enzyme replacement therapies. It validates the activity of alpha-mannosidase in leukocytes and tissue samples.
Features
Specific substrate cleavage; Screening for alpha-mannosidosis and lysosomal function.
Process Relevance
Lysosomal Function Research
Application Stage
Diagnosis / Research
Applications
Lysosomal storage disease (Mannosidosis) screening.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Lysosomal Storage Disorders
Datasheet