mTORC1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR75
Cell Type: DCs
RNA writers: NSUN6
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: ALKBH5
RNA types: mRNAs
Modification: m5C
RNA editing: G to A
Short Description
This product is a mTORC1-targeted RNA modification and metabolomics analysis tool based on the m5C (NSUN6-YTHDF2-TET1/2/3-ALKBH5-spacer C9) modification and Mevalonate pathway-mediated (FUS-Succinyl-CoA-ADP) metabolic analysis system.
RNA writers
NSUN6
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
ALKBH5
RNA types
mRNAs
Modification
m5C
Label
spacer C9
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
mRNAs-m5C-NSUN6-YTHDF2-TET1/2/3-ALKBH5-spacer C9
Substrates
Succinyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
KDM5A overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Breast Cancer
RNA-binding proteins
FUS
Metabolic Reprogramming
Mevalonate pathway-FUS-Succinyl-CoA-ADP
Target
mTORC1
Alternative Names
mTORC1 heteromer; mTORC1
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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