OGDH-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR48
Cell Type: M1 macrophages
RNA writers: DNMT2
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: ACOT12
RNA types: rRNA
Modification: m1A
RNA editing: A to I
Short Description
This product is a OGDH-targeted RNA modification and metabolomics analysis tool based on the m1A (DNMT2-ALYREF-ALKBH1-ACOT12-phos) modification and Mevalonate pathway-mediated (hnRNPs-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
ACOT12
RNA types
rRNA
Modification
m1A
Label
phos
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
rRNA-m1A-DNMT2-ALYREF-ALKBH1-ACOT12-phos
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Lung Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Lactyl-CoA-ADP
Target
OGDH
Alternative Names
OGDH; AKGDH; E1k; OGDC; oxoglutarate dehydrogenase; KGD1; OGDH2; OGDHD
Gene ID
4967(Human); 18293(Mouse); 360975(Rat)
UniProt ID
Q02218(Human); Q60597(Mouse); Q5XI78(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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