MDH2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR50
Cell Type: M1 macrophages
RNA writers: NSUN4
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: PDH
RNA types: mRNAs
Modification: m6A
RNA editing: A to I
Short Description
This product is a MDH2-targeted RNA modification and metabolomics analysis tool based on the m6A (NSUN4-YTHDF2-TET1/2/3-PDH-Hexynyl) modification and Gluconeogenesis-mediated (RBM9-SAM-ADP) metabolic analysis system.
RNA writers
NSUN4
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
PDH
RNA types
mRNAs
Modification
m6A
Label
Hexynyl
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m6A-NSUN4-YTHDF2-TET1/2/3-PDH-Hexynyl
Substrates
SAM
Cofactors
ADP
Pathway
Gluconeogenesis
Epigenetic regulator
NSD2 overexpression
Metabolic alteration
Upregulating pentose phosphate pathway
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
RBM9
Metabolic Reprogramming
Gluconeogenesis-RBM9-SAM-ADP
Target
MDH2
Alternative Names
MDH2; M-MDH; MDH; MGC:3559; MOR1; Malate dehydrogenase 2; EIEE51; DEE51
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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