OncoIHC™ YTHDF2 Ready-To-Use IHC Kit

Facilitate YTHDF2 detection using this ready-to-deploy IHC solution, encompassing reagents from antigen retrieval to slide preparation.

YTHDF2, also known as YTH domain-containing family protein 2, is a 579 amino acid protein with 1 YTH domain. It specifically binds m6A-containing RNAs and regulates mRNA stability. YTHDF2 promotes mRNA decay by binding m6A-containing mRNAs and localizing to processing bodies (P-bodies). It also facilitates cap-independent mRNA translation during heat shock stress, promoting translation initiation and protecting mRNAs from demethylation by FTO.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

YTHDF2

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 611
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

CLL associated antigen KW 14; HGRG8; NYREN2; YTH domain family protein 2; YTH domain family member 2; YTHDF2

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)