OXPHOSight™ Creatinine Assay Kit

CAT#: ITS-1125-HM18
Product Type: Assay Kit
Species: All Species
Brand: OXPHOSight
Development Stage: Research-Grade Metabolic Assay Development
Short Description
Measures creatinine levels to assess glomerular filtration rate.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Creatinine Assay Kit offers superior sensitivity for measuring glomerular filtration rate (GFR), essential for identifying nephrotoxic side effects in early drug candidates. Optimized for micro-volume samples, it surpasses traditional methods in detecting subtle changes in kidney function. This assay is a vital component of renal clearance studies and nephrotoxicity screening in pre-clinical development.
Features
Enhanced sensitivity surpasses traditional Jaffe methods; Optimized for micro-volume samples in renal clearance and nephrotoxicity studies.
Process Relevance
Nephrotoxicity Screening
Application Stage
Pre-clinical Safety
Applications
Key tool for evaluating kidney function offering higher sensitivity than the Jaffe method.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm; Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Urine, serum, plasma, and other biological preparations
Research Areas
Nephrology; Toxicology
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 60 min
LOD
Colorimetric: 4.8 µM (0.054 mg/dL);
Fluorimetric: 0.25 µM (0.0028 mg/dL)
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Creatinine is a breakdown product of creatine phosphate in muscle produced at a constant rate. It is filtered by the kidneys and excreted in urine; serum creatinine levels are the most commonly used indicator of renal function and glomerular filtration rate (GFR).
For Research Use Only | Not For Clinical Use
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